Researchers got a first look at microbes that inhabit the colonic mucosa. Pictured, from left, University of Illinois animal sciences and Institute for Genomic Biology professor Rex Gaskins, animal sciences visiting research specialist Ann Benefiel, Carle Foundation Hospital gastroenterologist Dr. Eugene Greenberg, and postdoctoral researcher Franck Carbonero.
Kolossov VL, Leslie MT, Chatterjee A, Sheehan BM, Kenis PJ, Gaskins HR. Förster resonance energy transfer-based sensor targeting endoplasmic reticulum reveals highly oxidative environment. Exp Biol Med, 2012, 237(6): 652-62. Epub 2012 Jun 19.
Croix JA, Bhatia S, Gaskins HR. Inflammatory cues modulate the expression of secretory product genes, Golgi sulfotransferases and sulfomucin production in LS174T cells. Exp Biol Med, 2011, 236 (12): 1402-12. Epub 2011 Nov 18.
Hong PY, Croix JA, Greenberg E, Gaskins HR, Mackie RI. Pyrosequencing-based analysis of the mucosal microbiota in healthy individuals reveals ubiquitous bacterial groups and micro-heterogeneity. PLoS One, 2011, 6 (9): e25042. Epub 2011 Sep 22.
Croix JA, Carbonero F, Nava GM, Russell M, Greenberg E, Gaskins HR. On the relationship between sialomucin and sulfomucin expression and hydrogenotrophic microbes in the human colonic mucosa. PLoS ONE, 2011, 6 (9): e24447. Epub Sep 9.
Nava GM, Ou J, Carbonero F, Croix JA, Greenberg E, and Gaskins HR. Abundance and diversity of mucosa-associated hydrogenotrophic microbes in the healthy human colon. ISME J, 2012, 6 (1): 57-70. Epub Jul 14 (doi: 10.1038/ismej).
Kolossov VL, Spring BQ, Clegg RM, Henry JJ, Sokolowski A, Kenis PJ, Gaskins HR. Development of a high-dynamic range, GFP-based FRET probe sensitive to oxidative microenvironments. Exp Biol Med, 2011, 236 (6):681-91. Epub 2011 May 23.
Lin C, Kolossov VL, Tsvid G, Trump L, Henry JJ, Henderson JL, Rund LA, Kenis PJ, Schook LB, Gaskins HR, Timp G. Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow. Integr Biol, 2011, 3 (3):208-17. Epub 2010 Dec 23.
Experimental Biology 2013
April 20-24, 2013, Boston, MA
Colonic Microbiota Distinguish Native Africans from African and European Americans
F Carbonero, GM Nava, J Ou, SJ O'Keefe, HR Gaskins
Winner of Best Young Scientist Poster Presentation
Abundance and distribution of mucosa-associated hydrogenotrophs in the healthy colon and in inflamed and non-inflamed tissues of IBD patients
F Carbonero, G Nava, J Croix, E Greenberg, HR Gaskins
Digestive Disease Week
May 18-21, 2013, Orlando, FL